Their lack of involvement in the starting lineup came as a major surprise as the two teams prepared to do battle for a place in the last eight.
Cheryshev, who has three goals so far in the tournament, was the victime of a change in system that saw Russia dpeloy wing-backs rather than wingers.
There were four changes from the defeat to Uruguay last time out, with Mario Fernandes, Yuri Zhirkov, Daler Kuzyaev and Aleksandr Golovin coming in for the suspended Igor Smolnikov and midfielders Aleksey Miranchuk, Yury Gazinsky and Cheryshev.
July 1, 2018
For Spain, there we three changes from the 2-2 draw with Morocco, though faith was kept with under-fire goalkeeper David De Gea.
Nacho replaced Real Madrid team-mate Dani Carvajal at right-back, with Koke in for Thiago Alcantara in midfield.
Iniesta also dropped out, being replaced by Marco Asensio as 'La Roja' named an attacking lineup.
July 1, 2018