Atletico Madrid were held to a goalless draw in Spain on Wednesday night despite having 20 shots.
Los Rojiblancos shot for goal 11 times in the first half and nine in the second against Lokomotiv goalkeeper Guilherme.
They also had 16 corners, the most of any side this season in the Champions League.
Despite their dominance, Atletico couldn't break the deadlock and now have just five points from a possible 12. They are second in Group A behind Bayern Munich and ahead of Lokomotiv on three - Salzburg prop up the group on one.