Arsenal have a terrible record at Old Trafford - they have won just once there in the league since 2006 - but they are facing a troubled United team who have lost their way under beleaguered boss Erik ten Hag.
If the Gunners fail to beat United, then City can wrap up an unprecedented fourth successive English title with a victory at Tottenham on Tuesday.
Even if Arsenal beat Erik ten Hag's men, City would still clinch a remarkable sixth title in seven seasons if they defeat Tottenham next week and see off West Ham at the Eithad Stadium on May 19. As a result, Mikel Arteta's men will have to give their all to stay in contention for the Premier League title and be sure not to make any mistakes in their final games.