Andres Iniesta
The Spaniard scored the goal that won his nation the World Cup back in 2010, but he announced prior to this year's tournament that 2018 was to be his final World Cup.
Gerard Pique
The 31-year-old centre-back also stated that this would be the last time he took part in a World Cup in the lead-up to Russia. He is yet to officially confirm this, but a disappointing showing from Spain means it is unlikely he will stay on.
David Silva
Manchester City's playmaker will be 36 by the time Qatar 2022 rolls around, meaning it is almost certain we won't be seeing another World Cup from Silva.
Javier Mascherano
The former Barcelona man announced his retirement in tears after Argentina were eliminated by France. The defensive midfielder racked up 147 caps for his country over his career.
Pepe
The 35-year-old was already pushing it a bit in Russia, but when the next tournament comes around he will be 39, meaning we won't see the defender at another World Cup.
Ricardo Quaresma
The same goes for Quaresma, who is just a year younger than Pepe.
Radamel Falcao
'El Tigre' will be 36 by 2022. He was able to bow out in style though, finally scoring a World Cup goal for his nation at the tournament.
Mario Gomez
The German forward will be 37 when the next World Cup begins. After a catastrophic showing from his nation, he is likely not the only member of the team who will retire from the international scene.
Messi?
The future of the Argentine star is as of yet unknown. Russia was billed as his last chance to add an international trophy to his cabinet, and he has already retired from the 'Albiceleste' once before. With his quality, it will be down to Leo himself to decide if he will play at another World Cup, but it doesn't look likely.
And...Ronaldo?
Unlike Messi, Ronaldo seems to thrive on being his nation's main man, and he is famed for being biologically younger than his age would suggest. However, he is yet to make any announcement about his international future, and he will be 37 by Qatar 2022.