Bayer Leverkusen coach Roger Schmidt has played down the significance of Lazio's absentees for Wednesday's Champions League play-off second leg.
Miroslav Klose (thigh) and Lucas Biglia (calf) are both set to miss the Serie A club's trip to the BayArena, which Lazio visit holding a 1-0 lead.
But Schmidt was unwilling to accept that his team were in some way favoured by the injuries and says the Italian side have shown that they can survive without them.
"I don't know whether it's an advantage," Schmidt said.
"Lazio played their last game last season against Napoli, in a very important match, without both players and they still won 4-2.
"I think Lazio have a good enough squad to compensate for that.
"Of course Biglia is a very important player for this team in certain situations, but I think, just as we're missing some players, Lazio will also be able to compensate for that.
"I don't think that will be decisive."
Despite being without two key men and carrying a lead to Germany, Lazio coach Stefano Pioli insists his team will attack.
"It's right to say we will try to attack whenever the chance arises," he said.
"We have to win the ball back as soon as possible, keeping Bayer away from our box because they are physical, skillful and talented in set-pieces.
"We have to be proactive in order to cause them problems as we have so much quality in our forwards. Fast players who are good in one-on-one situations.
"Let's exploit our skills and again, play with the spirit and focus that let us get here. That is, play to win."