The Portuguese made sure that he maintained his record of scoring in every champions League game so far this season in Cyprus to nod home Real's fifth and sixth goals of the night.
First, Marcelo was awarded far too much space down the left and when he crossed there was only ever going to be one winner.
Ronaldo rose highest at the far post and headed the ball back across Nauzet and into the far corner.
Not content with that, the 32-year-old added to his tally just five minutes later, tucking a loose ball into the net after Benzema had almost pounced on a poor backpass.
Check out the goals for yourself below:
GOAL! Who else but Ronaldo? 5-0! #RealMadrid #HalaMadrid #RMUCL #UCL #ChampionsLeague #APOEL #Ronaldo pic.twitter.com/DX6b8MGLb5
— Season Over October (@fantastachi) 21 November 2017
GOAL! And that's his weak foot... 6-0! #RealMadrid #HalaMadrid #RMUCL #UCL #ChampionsLeague #APOEL #Ronaldo pic.twitter.com/XLtNYmMQdo
— Season Over October (@fantastachi) 21 November 2017