England's World Cup final hopes were put in danger after Perisic was able to flick home a goal for Croatia.
Croatia has been turning up the heat on England in the second half, enjoying the majority of chances, as well as more possession.
Vrsaljko, who was deep on the right, driving towards the England box, was able to curl in a cross.
Walker ducked his head to clear the ball, but Perisic is able to get there before him, getting his foot high, and flicked the ball on.
Pickford dived, but was unable to make contact with the ball, as it dropped into the bottom left of the net.
Croatia 1-1 England.